How It Works
Retrain Your Jaw with Smart Biofeedback
Most mouthguards protect your teeth but don't change the underlying behavior. Zerene® trains your brain to stop grinding.
A small sensor detects the moment you clench, sends a gentle vibration, and over time your jaw learns to let go automatically, while you sleep.
Who It’s For
Built for people who've tried everything
You've done the boil-and-bite guards. Maybe you've tried Botox. You've probably woken up more mornings than you can count with a sore jaw, or a tension headache, and the sinking feeling that nothing is actually going to fix this.
Zerene isn't another thing to tolerate at night. It's a system designed to address the root cause of grinding, not just put a barrier between your teeth while it happens.
Everything you need to study, train, and maintain — in one thoughtfully designed system
Moon Module™
The brain of the Zerene system. This small, patented module connects to your mouthguard so the electronics never touch your teeth or tongue. It detects clenching at the source, measuring pressure in real time with precision most devices can't match. And weighing just 10 grams, it feels like it's barely there.
Custom Mouthguard
Thin, soft, and professionally fabricated from your impression. Not a boil-and-bite. A fully customized guard that stays put and feels comfortable.
Zerene App
Track your Z-Score™, bite strength (weak, medium, hard), and clenching/grinding trends. See the data. Watch yourself improve. Included free for 90 days.
Live Coaching & Human Support
Your own support team. Your Zerene coach monitors your data, checks in on your progress, and helps you make sense of what you're seeing so you're never left wondering what to do next.
Impression Kit
Custom fit starts here. Take impressions at home, ship them back, and receive your lab-made guard. No dentist appointments required.
$349
Free shipping · 100% money-back guarantee
Order Your KitIncludes 90 days of app access & coaching.
$29.99/6 months after that.
Three Phases, One Goal
How Zerene Teaches Your Jaw to Rest
Zerene doesn't just give you a device and wish you luck. It walks you through a structured program that's guided by your own data every step of the way.
Before Zerene can train you, it needs to understand you.
In Study Mode, you wear the device without any biofeedback activated. The Moon Module collects data while you sleep, measuring how often you clench, how hard, and when during the night it tends to happen. You wake up, open the app, and for the first time you actually see what's been happening to your jaw.
Some people discover they're clenching dozens of times a night with intense force. Others find it's more frequent but lighter. Either way, you'll know exactly what you're working with — and so will your coach.
What the app shows you:
- Your baseline Z-Score (your starting point)
- Bite frequency and strength (weak, medium, or hard)
- A nightly breakdown of clenching activity
This is the data that makes everything that follows more effective.
This is where the change happens. Most users see significant results within 2–3 weeks.
Once your baseline is established, Training Mode activates the biofeedback. Now, when the Moon Module detects a clench, it sends a gentle vibration: subtle enough not to fully wake you, but strong enough for your brain to register it. Over time, your jaw learns to release. The clenching that used to happen automatically, unconsciously, begins to diminish.
You don't have to do anything in your sleep. Your brain does the work.
As the nights add up, you'll watch your Z-Score trend downward in the app. Your coach will check in, help you interpret what the data is telling you, and adjust your approach if needed. This isn't an algorithm sending you generic push notifications. It's a real person who knows your data and cares about your results.
Most users notice a difference within two weeks. Some see up to 90% reduction in grinding activity within three.
What the app shows you:
- Z-Score trend graph (watch it drop)
- Night-by-night bite strength comparison
- Coach messages and progress notes
The graduation moment.
This is what no mouthguard has ever been able to offer you: the finish line.
When your data confirms your results are holding — when your Z-Score stays consistently low and your jaw has learned to rest on its own — you enter Maintenance Mode. You no longer need to wear Zerene every night. You wear it occasionally, during stressful stretches or whenever you want a check-in, and that's it.
The traditional mouthguard is a lifelong sentence. Zerene is a training program with an exit.
Leave the grind behind, and meet your new reality.
Real coaches help you get your best results with Zerene, so you never have to figure this out alone.
Your Zerene Coach is with you throughout your entire journey. Each day, they review your overnight data: your Z-Score trend, how your jaw is responding to the biofeedback, and whether your training needs to be adjusted.
This isn't an algorithm sending you generic push notifications. It's a real person who understands your goals and makes decisions based on your data.
Your coach is thinking about:
- The solutions you've tried before and what hasn't worked
- Whether your bite sensitivity threshold needs to be raised or lowered
- What your night-by-night data reveals about your progress
- How to keep your training moving forward if results plateau
Your coach is not AI. They're a member of the Zerene team who shows up for you every day — because getting your jaw to stop grinding for good takes more than a device. It takes someone in your corner.
Your Timeline
Your Journey to Better Mornings
No prescription required. FSA/HSA reimbursement eligible. Free shipping included.
Your custom mouthguard starts with a simple at-home impression. The kit is included in your order. Takes about 10 minutes.
Your custom-fit mouthguard and Moon Module arrive ready to use. For first-time setup, you'll visit zerenelife.com/welcome from a tablet or computer to get everything configured.
Wear the device for 3–5 nights to establish your baseline. No biofeedback yet, just data collection.
Biofeedback activates. You start retraining your jaw. Your coach is with you throughout.
Most users experience significant reduction in grinding activity. Your Z-Score trends downward. Your mornings start to feel different.
Your jaw has learned to rest. You wear Zerene only when you need a tune-up. You're done with nightly guards, for good.
The Science
Why Biofeedback Works
Grinding happens while you sleep, which means you can't consciously control it. Zerene works by detecting the moment clenching begins and sending a gentle vibration: a cue your brain learns to respond to over time. With repetition, your jaw muscles begin to relax automatically, even without the device. It's the same principle used in clinical biofeedback therapy, now available in a system you use at home.
Biofeedback has decades of clinical research behind it. See how it compares to night guards, Botox, and other treatments, and explore what the science says about why retraining works.
The Zerene App
Visualize Your Progress
No guessing. No wondering if it's working. Just clear, straightforward data every morning.
The Zerene app turns a night of sleep into something you can actually learn from. It's designed to feel like a coaching dashboard with everything built around one idea: your data should give you confidence, not confusion.
Daily Z-Score
Your nightly report card. The Z-Score combines bite duration and intensity against your total sleep hours to give you one clear number. Lower is better. Watch it drop.
Bite Strength Chart
See exactly how hard you're clenching and whether it's improving. Bites are categorized as weak, medium, or hard, so you can spot patterns and triggers over time.
"The device is comfortable to wear, and has significantly reduced my jaw pain and discomfort with remarkably durable effect – after a month of use I now find I only need to use it a couple of nights a week."
— Michael M.
Comfortable & Compatable
The Mouthguard You'll Actually Keep In
A mouthguard you spit out at 2am isn't protecting you, and it definitely isn't training you. Zerene's custom fit and thoughtful design exist specifically to solve the comfort problem that OTC guards never could.
Here's what makes it different:
- The Moon Module and mouthguard together weigh 10 grams, or about as much as two nickels. You'll forget it's there.
- Your custom-fit, lab-made mouthguard is made from an impression of your actual teeth, not a generic mold heated in a cup of hot water.
- The Moon Module, the part with all the electronics, stays outside your mouth. You get the intelligence of a smart device without any of the bulk or discomfort inside.
- Thin, soft material is designed to be unobtrusive enough that side sleepers and restless sleepers can keep it in all night.
- CPAP compatible: if you're already managing sleep apnea, Zerene can work alongside your CPAP setup without interference.
- No medication, no injections, no side effects.
Wake up as yourself again.
Zerene can help you stop grinding.
100% money-back guarantee · HSA/FSA reimbursement eligible · Ships to US